Prof James is a Professor in Cancer Immunology and Associate Dean for Infrastructure in the Faculty of Medicine at the University of Southampton. He established his group in 2006 and now leads a team that focuses on understanding the mechanisms behind the immunodominance of antigens in tumours and the impact on anti-tumour T cell responses. In addition, his team investigates the role antigen processing and presentation plays in generating immune responses and how these processes can be modulated for therapeutic benefit.